Marketers often promote kratom as a ‘natural’ remedy for pain relief, energy boosts, or opioid withdrawal support. However, many people fail to recognize that one of kratom’s most potent ingredients, 7-hydroxymitragynine (7-OH), can trigger severe dependence and serious withdrawal symptoms.

If you or someone you care about is struggling to stop using kratom, you're not alone. At The Coleman Institute, we specialize in helping people detox from kratom and 7-OH safely, quickly, and more comfortably, usually in just 5 days, through our unique Outpatient Kratom Detox Program.

What Is 7-Hydroxymitragynine (7-OH)?

7-hydroxymitragynine is a naturally occurring alkaloid found in the leaves of the kratom plant (Mitragyna speciosa). Although it makes up a small percentage of the plant's total alkaloid profile, it's responsible for the majority of kratom's opioid-like effects.

Why? Studies show 7-OH to be up to 13 times more potent than morphine in terms of how it interacts with the brain's mu-opioid receptors. This makes 7-hydroxymitragynine highly addictive.

While kratom products were once limited to raw leaf powder, today's market includes highly concentrated extracts, enhanced blends, and other labeled 7-OH products, many of which are openly marketed in smoke shops and online. Consequently, these versions can contain significantly more 7-OH than occurs naturally in the plant, increasing the risk of dependence and making quitting even more challenging. Moreover, the popularity of other kratom-based formulas, such as pseudo (pseudoinoxyl) and nano kratom, has been on the rise.

How Is 7-OH Consumed?

Typically, 7-OH is consumed in forms such as:
  • Kratom capsules or powder - containing trace amounts of 7-OH
  • Concentrated extracts or shots - significantly more potent
  • 'Enhanced' kratom blends - fortified with added 7-OH
  • Smoke shop products - often marketed specifically for 7-OH content
  • Synthetic blends - sometimes found in unregulated online supplements
While some people use kratom occasionally, many find themselves needing to use more and more often to achieve the same effects, a sign of increasing tolerance and dependence.

What Do 7-OH Withdrawals Feel Like?

Over time, as the body adapts to the presence of 7-hydroxymitragynine, quitting kratom can cause a wide range of opioid-like withdrawal symptoms, including:
  • Anxiety, restlessness, & irritability
  • Insomnia & racing thoughts
  • Muscle aches, chills, & tremors
  • Nausea, vomiting, & diarrhea
  • Depression & mood swings
  • Fatigue & intense cravings
However, many people attempt to quit 'cold turkey' and find themselves overwhelmed by how difficult it is, especially if they've been using high-potency products.

Outpatient Kratom Detox at The Coleman Institute

At The Coleman Institute, we've developed a specialized outpatient detox program that is tailored specifically to people dependent on kratom and 7-OH. Our Kratom Detox Program typically takes just 5 days to complete without the need for inpatient rehab or hospitalization.

What to Expect:

  • Medical Safety & Comfort
    • Experienced medical professionals manage your detox and use non-addictive comfort medications to reduce withdrawal symptoms.
  • Outpatient Convenience
    • Most patients complete detoxification in five days, instead of struggling with withdrawal for weeks or months. No overnight stay needed with our accelerated method.
  • Customized Protocol
    • We tailor every detox to the individual’s needs.
  • Naltrexone Therapy (Optional Post-Detox)
    • After detox, we offer the option to begin Naltrexone Therapy, a non-addictive, FDA-approved medication that helps reduce cravings and support long-term recovery. You can take naltrexone as a daily tablet or receive it as a monthly injection.
Chronic use of 7-OH products can cause withdrawal symptoms similar to opioids. this includes nausea, anxiety, cravings, & insomnia.

Why Choose The Coleman Institute?

We understand how isolating and frustrating it can be to feel stuck in a cycle of dependence.

Overall, our Kratom Detox Program is designed to be:
  • Fast - Most detoxes are complete in just five days
  • Safe - Medically supervised & individualized care
  • Comfortable - We use non-addictive, comfort-based medications
  • Outpatient - No residential rehab or hospital stay required
  • Evidence-Based - Backed by over 25 years of clinical experience and a 95% completion rate
Ultimately, The Coleman Institute focuses on helping you move forward from addiction with confidence, clarity, comfort, and compassion.

Kratom Use Disorder negatively affects both your physical & mental health.

Ready to Break Free from Kratom & 7-OH?

In sum, kratom may be legal and plant-derived, but 7-hydroxymitragynine (7-OH) acts on the brain like a powerful opioid, and quitting without help can be extremely hard. You don't have to navigate this alone.

At The Coleman Institute, our team is here to support you every step of the way with a 5-day outpatient detox program that's safe, comfortable, effective, and non-disruptive to your life.

Learn more about our Kratom Detox by visiting our webpage or calling to speak with a compassionate member of our team.